BS ISO 18664:2015 pdf free.Traditional Chinese Medicine – Determination of heavy metals in herbal medicines used in Traditional Chinese Medicine.
BS ISO 18664 specifies determination methods of lead (Pb), arsenic (As), cadmium (Cd) and mercury (Hg) in herbal medicines used in Traditional Chinese Medicine (TCM). It is applicable to natural materials of TCM that are sold and used as food supplements, functional foods or natural medicines in international trade, including Chinese materia medica (whole medicinal materials) and decoction pieces derived from plants or animals. It is not applicable to mineral drugs used in TCM.
This International Standard is not intended to set maximum limits (ML) for individual nations; rather, it is intended to give a reference for standardized testing method and risk assessment.
2 Normative references
The following documents, in whole or in part, are normatively referenced in this document and are indispensable for its application. For dated references, only the edition cited applies. For undated references, the latest edition of the referenced document (including any amendments) applies.
ISO 6561-2:2005. Fruits, vegetables and derived products — Determination of cadmium content — Part 2: Method using flame atomic absorption spectrometry
ISO 11212-1:1997, Starch and derived products — Heavy metals content — Part 1: DetermInation of arsenic content by atomic absorption spectrometry
ISO 11212-2:1997, Starch and derived products — heavy metals content — Part 2: Determination of mercury content by atomic absorption spectrometry
ISO 11212-3:1997, Starch and derived products — Heavy metals content — Part 3: Determination of lead content by atomic absorption spectrometry with electrothermal atomization
ISO 11212-4:1997, Starch and derived products — Heavy metals content — Part 4: Determination of cadmium content by atomic absorption spectrometry with electrothermal atomization
ISO 11885:2007, Water quality — Determination of selected elements by inductively coupled plasma optical emission spectrometry (ICP-OES)
ISO 17239:2004, Fruits, vegetables and derived products — Determination of arsenic content — Method using hydride generation atomic absorption spectrometry
ISO 17294-1:2004, Water quality — Application of inductively coupled plasma ‘floss spectrometry (ICPMS) — Part 1: General guidelines
ISO 17294-2:2003, Water quality — Application of inductively coupled plasma moss spectrometry (KYMS) — Part 2: Determination of 62 elements
ISO/TS 21033:2011, Animal and vegetable fats and oils — Determination of trace elements by inductively coupled plasma optical emission spectroscopy (ICP-OES)
ISO 27085:2009, Animal feeding stuffs — Determination of calcium, sodium, phosphorus, magnesium, potassium, iron, zinc, copper, manganese, cobalt, molybdenum, arsenic, lead and cadmium by lcP-AES
3 Terms and definitions
For the purposes of this document, the following terms and definitions apply.
3.1 arsenic content quantity of arsenic determined in accordance with the conditions specified in this method and expressed as arsenic (As), in micrograms per kilogram of the product as received[SOURCE: ISO 11212-1:1997, 2.1]
3.2 mercury content quantity of mercury determined in accordance with the conditions specified in this method and expressed as mercury (Hg), in micrograms per kilogram of the product as received [SOURCE: ISO 11212-2:1997, 2.11
3.3 lead content quantity of lead determined in accordance with the conditions specified in this method and expressed as lead (Pb), in micrograms per kilogram of the product as received [SOURCE: ISO 11212-3:1997, 2.11
3.4 cadmium content quantity of cadmium determined in accordance with the conditions specified in this method and expressed as cadmium (Cd), in micrograms per kilogram of the product as received [SOURCE: ISO 11212-4:1997, 2.1]
4 Analytical methods
4.1 Instrumental methods
4.1.1 Atomic Absorption Spectrometry (AAS)
AAS methods can be used for the individual determination of lead, mercury, arsenic and cadmium in natural materials used in TCM. The detailed information is specified in the following documents.BS ISO 18664 pdf download.